Recognized families of pathogenesis-related proteins

Families
Type member
Properties
Gene symbol
Reference
PR-1 Tobacco PR-1a antifungal Ypr1 Antoniw et al., 1980
PR-2 Tobacco PR-2 b-1,3-glucanase Ypr2, [Gns2 ('Glb')] Antoniw et al., 1980
PR-3 Tobacco P, Q chitinase type I,II, IV,V,VI,VII Ypr3, Chia Van Loon, 1982
PR-4 Tobacco 'R' chitinase type I,II Ypr4, Chid Van Loon, 1982
PR-5 Tobacco S thaumatin-like Ypr5 Van Loon, 1982
PR-6 Tomato Inhibitor I proteinase-inhibitor Ypr6, Pis ('Pin') Green and Ryan, 1972
PR-7 Tomato P69 endoproteinase Ypr7 Vera and Conejero, 1988
PR-8 Cucumber chitinase chitinase type III Ypr8, Chib Métraux et al., 1988
PR-9 Tobacco 'lignin-forming peroxidase' peroxidase Ypr9, Prx Lagrimini et al., 1987
PR-10 Parsley 'PR1' 'ribonuclease-like' Ypr10 Somssich et al., 1986
PR-11 Tobacco 'class V' chitinase chitinase, type I Ypr11, Chic Melchers et al., 1994
PR-12 Radish Rs-AFP3 defensin Ypr12 Terras et al., 1992
PR-13 Arabidopsis THI2.1 thionin Ypr13, Thi Epple et al., 1995
PR-14 Barley LTP4 lipid-transfer protein Ypr14, Ltp García-Olmedo et al., 1995
PR-15 Barley OxOa (germin) oxalate oxidase Ypr15 Zhang et al., 1995
PR-16 Barley OxOLP 'oxalate oxidase-like' Yrp16 Wei et al., 1998
PR-17 Tobacco PRp27 unknown Yrp17 Okushima et al., 2000

       

  General references:

Van Loon, L.C., Pierpoint, W.S., Boller, T. and Conejero, V. 1994. Recommendations for naming plant pathogenesis-related proteins. Plant Mol. Biol. Reporter 12: 245-264.

Van Loon, L.C. and Van Strien, E.A. 1999. The families of pathogenesis-related proteins, their activities, and comparative analysis of PR-1 type proteins. Physiol. Mol. Plant Pathol. 55: 85-97.

 

  Specific references:

Antoniw, J.F., Ritter, C.E., Pierpoint, W.S. and Van Loon, L.C. 1980. Comparison of three pathogenesis-related proteins from plants of two cultivars of tobacco infected with TMV. J. Gen. Virol. 47: 79-87.

Epple, P., Apel, K. and Bohlmann, H. 1995. An Arabidopsis thaliana thionin gene is inducible via a signal transduction pathway different from that for pathogenesis-related proteins. Plant Physiol. 109: 813-820.

García-Olmedo, F., Molina, A., Segura, A. and Moreno, M. 1995. The defensive role of nonspecific lipid-transfer proteins in plants. Trends Microbiol. 3: 72-74.

Green, T.R. and Ryan, C.A. 1972. Wound-induced proteinase inhibitor in plant leaves: a possible defense mechanism against insects. Science 175: 776-777.

Lagrimini, L.M., Burkhart, W., Moyer, M. and Rothstein, S. 1987. Molecular cloning of complementary DNA encoding the lignin-forming peroxidase from tobacco: molecular analysis and tissue-specific expression. Proc. Natl. Acad. Sci. USA 84: 7542-7546.

Melchers, L.S., Apotheker-de Groot, M., Van der Knaap, J.A., Ponstein, A.S., Sela-Buurlage, M.B., Bol, J.F., Cornelissen, B.J.C., Van den Elzen, P.J.M. and Linthorst, H.J.M. 1994. A new class of tobacco chitinases homologous to bacterial exo-chitinases displays antifungal activity. Plant J. 5: 469-480.

Métraux, J.-P., Streit, L. and Staub, Th. 1988. A pathogenesis-related protein in cucumber is a chitinase. Physiol. Mol. Plant Pathol. 33: 1-9.

Okushima, Y., Koizumi, N., Kusano, T. and Sano, H. 2000. Secreted proteins of tobacco cultured BY2 cells: identification of a new member of pathogenesis-related proteins. Plant Mol. Biol. 42: 479-488.

Somssich, I.E., Schmelzer, E., Bollmann, J. and Hahlbrock, K. 1986. Rapid activation by fungal elicitor of genes encoding "pathogenesis-related" proteins in cultured parsley cells. Proc. Natl. Acad. Sci. USA 83: 2427-2430.

Terras, F.R.G., Schoofs, H., De Bolle, M.F.C., Van Leuven, F., Rees, S.B., Vanderleyden, J., Cammue, B.P.A. and Broekaert, W.F. 1992. Analysis of two novel classes of plant antifungal proteins from radish (Raphanus sativus L.) seeds. J. Biol. Chem. 267: 15301-15309.

Van Loon, L.C. 1982. Regulation of changes in proteins and enzymes associated with active defense against virus infection. In: Active Defense Mechanisms in Plants (R.K.S. Wood, ed.), pp. 247-273, Plenum Press, New York, USA.

Vera, P. and Conejero, V. 1988. Pathogenesis-related proteins of tomato. P-69 as an alkaline endoproteinase. Plant Physiol. 87: 58-63.

Wei, Y., Zhang, Z., Andersen, C.H., Schmelzer, E., Gregersen, P.L., Collinge, D.B., Smedegaard-Petersen, V. and Thordal-Christensen, H. 1998. An epidermis/papilla-specific oxalate oxidase-like protein in the defence response of barley attacked by the powdery mildew fungus. Plant Mol. Biol. 36: 101-112.

Zhang, Z., Collinge, D.B. and Thordal-Christensen, H. 1995. Germin-like oxalate oxidase, a H2O2-producing enzyme, accumulates in barley attacked by the powdery mildew fungus. Plant J. 8: 139-145.