Faculteit Biologie: Molecular Genetics: GPB index

<body>  <table id="main" width="750" border="0" cellspacing="0" cellpadding="0" summary="Content"> <tr> <td valign="top" height="250"> <p align="justify"></td> <td valign="top" id="content"> <h2 align="justify"><span style="font-size: 15pt" lang="en-us"><br> Genomics, Proteomics and Bioinformatics</span></h2> <p align="justify"><br> <span lang="en-us"><b> <a href="microarray_facility/index.html">Arabidopsis Microarray Facility</a></b></span></p> <p align="justify"><font color="#804040"> <span lang="EN-GB" style="font-size: 9pt; font-family: Arial"> <img border="0" src="images/CATMAlogo.jpg" width="114" height="90" align="right"></span></font><font face="Verdana"><span lang="EN-GB" style="font-size: 9pt; ">The genomics facility is involved in the production of the CATMA DNA microarray and facilitates the use of microarrays for the end-user by providing access to genomics equipments and data analysis tools.</span></font><span style="font-size: 9pt; font-family: Verdana" lang="en-us"> More information about ordering and use of CATMA DNA microarray slides can be found<font color="#804040"> <a href="microarray_facility/index.html"> <u>here</u></a>.</font></span></p> <p align="justify"><span lang="en-us"><b><font face="Arial"><br> </font><font face="Verdana"><span style="font-size: 9pt"><a name="CAGE">CAGE: <i>C</i>ompendium for <i>A</i>rabidopsis <i>G</i>ene <i>E</i>xpression</a></span></font></b></span></p> <p align="justify"><span lang="en-us"><font face="Verdana"> <span style="font-size: 9pt">T</span></font></span><span style="color: black; font-family: Microsoft Sans Serif"><font face="Verdana"><span style="font-size: 9pt">he <span lang="en-us">goal of the </span>CAGE consortium <span lang="en-us">is </span>to build a gene expression reference database for Arabidopsis by making use of the Complete Transcriptome MicroArray (CATMA). A compendium of gene expression profiles will be made of samples taken from phenotype-based time series of <i> Arabidopsis thaliana</i> and a collection of landmark mutants.</span><span style="font-size: 9pt" lang="en-us">  For more information about this project: <a target="_blank" href="http://www.psb.ugent.be/CAGE/"><u>CAGE homepage</u></a></span></font></span></p> <p align="justify"><span lang="en-us"><b><br> <a name="Bioinformatics">Bioinformatics</a></b></span></p> <p align="justify"><span lang="en-us">Bioinformatics research at the Molecular Genetics Department focuses on Arabidopsis transcription networks. In addition we offer in house bioinformatics tools for prediction of gene and protein function. Moreover general tools such as a BLAST server, a LIMS system, etc. can be found at <a target="_blank" href="http://genomics.bio.uu.nl/"> http://genomics.bio.uu.nl</a>. For more information or questions contact our Bioinformaticist:<br> <a target="content" href="members/Henk.html">Drs. Henk van den Toorn</a></span></p> <p align="justify"><span lang="en-us"><b><br> <a name="Proteomics">Proteomics</a></b></span></p> <p align="justify"><span lang="en-us">Several of the projects carried out at our laboratory involve a proteomics approach. The proteomics part of these studies is carried out in collaboration with the <a target="_blank" href="http://www.chem.uu.nl/bioms/">Department of Bio-Molecular Mass Spectrometry</a> of Prof. Dr. Albert Heck, of the Faculties of Pharmacy and Chemistry, University Utrecht. To achieve our goals we use state-of-the-art Mass Spectrometry techniques like LC-MS-MS and MALDI-ToF mass spectrometry to identify proteins involved in various plant-pathogen related processes.</span></p> <p align="justify"><u><span lang="en-us">Projects:</span></u></p> <h2 align="justify"> <a target="content" href="../pmg/research/interface.html"> <span style="font-size: 9pt"><font face="Verdana" color="#804040">Signaling at the host-microbe interface:</font></span><span lang="en-us"><font face="Verdana" color="#804040"> </font> </span> <span style="font-size: 9pt; font-weight:400" lang="en-us"> <font face="Verdana" color="#804040">P</font></span><span style="font-size: 9pt; font-weight:400"><font face="Verdana" color="#804040">athogen-induced modulation of the plant plasma membrane</font></span></a></h2> <p align="justify"><span lang="EN-GB"> <a href="../pst/research/Project1.html"> <font color="#804040" face="Verdana" style="font-size: 9pt">A functional proteomics approach to identify phospho-proteins involved in plant innate immunity</font></a></span></td> </tr> <tr> <td height="50"> <p align="justify"></td> <td align="left" valign="bottom"> <div class="teklein"> <p align="justify"><a target="_self" href="#_Top"> <img border="0" src="images/solis/pijl-up.gif" align="right" width="25" height="28" /></a><a href="cnt.html" target="_self"> </a> Last update: 29-Sep-2005<br /> <a href="mailto:N.W.Boot@bio.uu.nl"><span lang="en-us"> <font face="Verdana" size="1" color="#804040">N.W.Boot</font></span><font face="Verdana" size="1" color="#804040">@bio.uu.nl</font></a></div> </td> </tr> <tr> <td> <p align="justify"><img src="images/tpix.gif" width="36" height="1" alt="" /></td> <td> <p align="justify"><img src="images/tpix.gif" width="714" height="1" alt="" /></td> </tr> </table>  </body>