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Molecular Genetics
For our research on development and host-microbe
genetics we have adopted the tiny "lab
weed" Arabidopsis thaliana as a model plant. Our groups focus on the following
research themes:
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Plant
Development
(Ben Scheres, Ikram Blilou, Renze
Heidstra, and Viola Willemsen)
Plant development depends largely on the
activity of small regions of continuous growth and development, the
meristems. The plant development group aims to understand better how
meristems work. We work mostly on root tips because the root meristem has a simple cellular
organization. |
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Plant-Microbe Genetics (Guido Van den Ackerveken)
The
molecular processes at the interface of host and pathogen determine if a
plant is resistant or susceptible. Our group aims to identify the
molecular players in this process and to understand their function.
Plant Defense Signaling (Frank Menke)
Plants possess
sophisticated defense mechanisms to counteract pathogens. We
study the genes and proteins involved in the
innate immune response of Arabidopsis. |
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Genomics,
Proteomics , and Bioinformatics
In our genomics lab we produce and use Arabidopsis DNA microarrays and
other custom arrays for expression profiling. Our proteomics research is
focussed on (i) Arabidopsis protein complexes involved in plant
development, (ii) phospo-proteins in innate immunity and (iii)
membrane-associated proteins functioning at the host-pathogen interface.
The genomics and proteomics studies are supported by bioinformatics,
which is focussed on the integration of the different types of -omics
data. |
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